This is giantess/shrink interactive based on Katawa Shoujo, a visual novel developed by 4Leaf Studios. Check it out if you haven't, you're probably going to want background info and it's a very entertaining, touching read, and it's free.
http://katawa-shoujo.com/
Hisao is a resident of Japan just settling into Yamaku, high school for the disabled after months of hospitalization from an
arrhythmia-related heart attack. Little does he know that an experimental medication he receives may have undesirable side effects...
Here's a basic outline of the main characters:
Lilly: Blind girl, half scottish, half Japanese, blond hair, pale blue eyes, taller than an average Japanese girl, has a caring, motherly attitude towards others and is very well-mannered and proper. Friend of Hanako. Feels tense towards Shizune due to past events.
Hanako: Burn victim, scars cover most of her body's right side but she's very cute besides, medium height, dark purple hair, extremely self-conscious and shy, tends to avoid others but enjoys games like chess and billiards. Friend of Lilly.
Shizune: Deaf and mute since birth, uses sign language, almost always with Misha in tow as an interpreter. Short blue hair, glasses. President of the Student Council. Aggressively daring, commanding, dominant, but cares for those who are willing to befriend her. Dislikes Lilly.
Misha: Interpreter, classmate, and long-time friend of Shizune. Pink hair, arranged in two 'drill' style curls. Slightly plump body. Very enthusiastic and energetic, often to the fault of seeming intrusive, never seems to stop smiling.
Emi: Lost her legs in a car accident when she was young. Light brown/orange hair in twin pigtails, short, very energetic and friendly towards others. Can be a little reckless at times. Member of the track team who loves to run. Friend to Rin, helps her with everyday activities like putting on clothes.
Rin: No arms. Medium-length burgundy hair. Loves to paint, does so using her feet. Simply aloof, calm, and carefree, she prefers to live in the moment and enjoy herself.
All above characters are high school seniors, ages 18-19.
More info, including pictures, can be found at the site linked above.
I'm going light on the rules but here's the basics:
-You may use any of the major or minor female characters or make up your own, but no bringing incharacters from other series. It's more than likely there's a better story for them to fit them into elsewhere
-Try not to go too off-kilter with established character personalities, but creative encounters are encouraged
Other than that, enjoy.
(final re-make, I promise! Errors seem to like to crop up if an interactive item isn't created just right. I'm sort of new at this, but it all looks like it's fixed now)